Abstract: Objective To explore the effect of mixed reality technology in the treatment of elderly osteoporotic thoracolumbar spine compression fractures.
Methods 66 elderly patients with osteoporotic thoracolumbar vertebral compression fractures were randomly selected from our hospital,which were randomly divided into two groups，33 in the experimental group and 33 in the control group.Percutaneous kyphoplasty was used in both groups.The experimental group was assisted by mixed reality equipment in the treatment，while the control group was traditional.Calculate the date of operation time，blood loss，accuracy of working cannula placement，number of fluoroscopy，bone cement leakage，and rehabilitation scores before and after treatment.
Results Through the reconstruction of three-dimensional model，the injection point can be accurately located and the operation process can be accurately guided.The operation time，the number of fluoroscopy times，and the leakage rate of bone cement in the experimental group were (38.97±7.81) min，(15.59±6.78) times，and 9.09%，respectively，which were significantly lower than those in the control group [(48.34±10.71) min，(29.39±9.19) times，and 27.27%].The differences were statistically significant (P<0.05).The Cobb  was (9.52±2.51)° in the experimental group was higher than that in the control group [(7.33±2.42)°],there was statistical significance (P<0.05).There were no significant differences and no statistical significance in other data(P>0.05).
Conclusion The application of MR technology in the treatment of elderly osteoporotic thoracolumbar vertebral compression fractures can effectively promote doctor-patient communication，reduce the number of fluoroscopy，shorten the operation time，restore Cobb angle better，and reduce the rate of bone cement leakage，which shows a broad application prospect.

Key words: mixed reality, osteoporosis, thoracolumbar spine, compression fracture, percutaneous kyphoplasty