Abstract: Objective To explore and analyze the risk factors of anastomotic leakage after esophageal cancer eradication.
Methods According to the occurrence of postoperative anastomotic leakage,300 patients underwent esophagectomy in our hospital from December 2016 to December 2018 were divided into anastomotic leakage group (84 cases) and non-anastomotic leakage group (216 cases).Univariate analysis,and logistic regression analysis was used to analyze the risk factors of anastomotic leakage after esophageal cancer eradication.
Results Univariate analysis showed that the main influencing factors of anastomotic leakage included operation mode,anastomotic position,preoperative radiotherapy and chemotherapy,serum albumin level,respiratory diseases and operation time.Logistic regression analysis showed that operation mode,anastomotic position,preoperative radiotherapy and chemotherapy,combined with respiratory diseases,operation time and albumin level were independent risk factors of anastomotic leakage after esophagectomy.
Conclusion There are many risk factors of anastomotic leakage after radical resection of esophageal cancer.Therefore,effective prevention and treatment measures should be made according to these independent risk factors.

Key words: esophageal cancer, radical operation, anastomotic leakage, risk factors