Abstract: Objective：To investigate the risk factors affecting the healing of diabetic lower extremity ulcers (DLEU).Methods：Clinical data of 95 patients with DLEU treated in Provincial Hospital Affiliated to Shandong First Medical University，Jinan Municipal Hospital of Traditional Chinese Medicine and Jinan People's Hospital from July 2015 to July 2018 were retrospectively analyzed.According to whether the ulcer cicatrized during the followup period，patients were divided into the healing group (45 cases) and unhealing group (50 cases)，independent risk factors affecting DLEU healing were analyzed using logistic regression analysis.Results：There was no significant difference in sex，age，glycosylated hemoglobin，body mass index，DLEU course，diabetes course，history of hypertension，operation mode，preoperative ankle brachial pressure index (ABI) and preoperative visual analogue score (VAS) between the two groups（P＞0.05）.However，the difference in the history of coronary heart disease，postoperative ABI，ulcer site and so on were statistically significant（P＜0.05）.Logistic regression showed that the history of coronary heart disease，postoperative ABI and ulcer site were independent risk factors for DLEU healing.Conclusion：Coronary heart disease，subnormal ABI and ulcer sites such as toe，acrotarsium，pelma and pretibial are independent risk factors for DLEU healing.

Key words: diabetic lower extremity ulcers, 〓cicatrization, 〓risk factor