Abstract: Objective To explore the effect of T-type full-mechanical lateral anastomosis（TSA）in the treatment of esophageal cancer. Methods 108 patients who underwent radical laparoscopic radical esophagectomy in our hospital from January 2016 to April 2018，were enrolled according to the order of admission.The patients were divided into the experimental group（with TSA anastomosis during surgery）and the control group（rounded during surgery）.The end-to-side anastomosis of the tubular anastomosis was performed in 54 cases.The surgical anastomosis time，postoperative hospital stay，surgical complications，anastomotic stenosis，and anastomotic area were compared between the two groups. Results The anastomosis time（17.4±2.1）min in the test group was significantly lower than that in the control group（25.8±3.0）min（P<0.05）.There was no significant difference in the postoperative hospital stay（13.8±2.0）days in the test group and（14.3±2.3）days in the control group（P>0.05）.The surgical complication rate of patients in the test group was 12.96% lower than that in the control group（37.04%）（P<0.05）；At 6 months after surgery，the incidence of anastomotic stenosis in the experimental group was 1.85% lower than that in the control group 14.81%，and the difference was statistically significant（P<0.05）；At 6 months after operation，the anastomosis area（2.17±0.30）cm2 in the test group was higher than that in the control group（1.90±0.28）cm2，and the difference was statistically significant（P<0.05）. Conclusion The use of left-neck T-type full-mechanical lateral anastomosis in esophageal cancer surgery can effectively shorten the time of anastomosis，reduce postoperative complications，and especially reduce the occurrence of anastomotic stenosis.

Key words: left neck, T-type full mechanical lateral anastomosis, esophageal cancer, circular tubular stapler