Abstract: Objective:To investigate the clinical effects and safety of fast track surgery（FTS）in the colon cancer patients with intestinal obstruction.Methods:The clinical data of 72 colon cancer patients with intestinal obstruction was collected and analyzed.The patients were divided into two groups：traditional group（36 cases）and FTS group （36 cases）by random number table method.The postoperative VAS score，first time out of bed，first exhaust time，first defecation time，first time，eating time and postoperative complications in hospital was collected and analyzed.Results:The VAS score of FTS group was significantly lower than that in the traditional group at the 1st and 3rd day after operation（P<0.05），but there was no significant difference between the two groups on the 7th day after operation（P>0.05）.The first time out of bed in 〖JP+1〗FTS group and traditional group was（17.66±12.10）h and（26.37±10.70）h，respectively；the first exhaust time was（47.54±15.30）h and（57.95±18.40）h，respectively；the firstdefecation time was（98.26±27.10）h and（115.63±27.50）h，respectively；the first inlet time was（48.72±13.50）h and（57.75±17.00）h，respectively；the discharging time was（5.85±2.2）d and（8.73±3.5）d，respectively.The difference between the two groups was statistically significant（P<0.05）.The incidence of postoperative pulmonary infection and incision infection in group FTS was less than that in traditional group（P<0.05）.Postoperative abdominal distention and vomiting in group FTS were significantly higher than those in traditional group（P<0.05）.There was no significant difference in postoperative complications such as intraperitoneal hemorrhage，intraperitoneal infection and anastomotic stenosis between the two groups（P>0.05）.Conclusion:FTS is a safe and effective method in colon cancer patients complicated with intestinal obstruction，and does not increase the risk of complications，which accelerates the postoperative rehabilitation and shortening hospital stays.

Key words: fast track surgery, colon cancer, intestinal obstruction