Abstract: Objective：To explore the clinical effect of prostate ultrasound in treating prostatic calculus.Methods：68 patients with prostatic calculi were divided into observation group（n=36）and control group（n =32）according to the final treatment，the observation group was given ultrasonic conductive microwave therapy，while the control group was given conventional treatment，the size of prostate stones and the International Erectile Function Index5 score and so on were observed before and after treatment.Results：1 and 3 months after treatment，the size of prostate stones in the observation group were（23.10±3.82）mm2 and（17.82±1.82）mm2，which were significantly lower than those in the control group（P<0.05）.The IIEF5 scores of the observation group at 1 month and 3 months after treatment were（16.29±2.70）and（13.82±1.91），which were significantly lower than those of the control group（P<0.05）；The maximal urinary flow rate at 1 month and 3 months after treatment in the observation group were（8.72±0.98）ml/s and（14.10±1.21）ml/s，were significantly higher than that in the control group（P<0.05），while the residual urine volume was（40.02±3.82）ml and（16.90±2.20）ml，were significantly lower than that in the control group（P<0.05）；The PSA of the observation group at 1 month and 3 months after treatment were（7.28±1.20）μg/L and（1.65±0.98）μg/L，were significantly lower than that of the control group（P<0.05）.Conclusion：Ultrasoundguided microwave treatment of prostate stones has a better effect，is conducive to improving sexual function，uresis function.

Key words: ultrasound guided microwave therapy, prostatic calculus, sexual function, uresis function