Abstract: Objective：To compare and analyze the combined effects and complications of 3D and 2D laparoscopic radical prostatectomy in the treatment of prostate cancer.Methods：Eightytwo patients undergoing laparoscopic radical prostatectomy from June 2015 to April 2017 were selected and divided into group I（3D laparoscopy）and group II（2D laparoscopy）according to the surgical approach.Each group had 41 cases，of which clinical data were retrospectively analyzed.The operation time，intraoperative blood loss，intraoperative nerve retention，urethral reconstruction time，surgical margin positive rate，and other surgical parameters were compared between the two groups.Patients were followed up for half a year and the postoperative urine was compared between the two groups.Incidence of incontinence，retention of erectile function success rate，postoperative biochemical recurrence rate，and other complications.Results：Compared with the 2D group，the operation time（61.35±16.45）min，the intraoperative blood loss（98.73±80.56）ml，and the urethral reconstruction time（23.65±11.39）min were significantly lower in the 3D group，the difference was statistically significant（P<0.01）.Compared with the 2D group，the positive rate of surgical margin（7.3%）was lower in the 3D group，but there was no statistically significant difference（P>0.05）.The incidence of postoperative urinary incontinence in patients in the 3D group（4.88%）was significantly lower than that in the 2D group（21.95%），the success rate of retention of erectile function（43.90%）was significantly higher than that in the 2D group（9.76%）.the biochemical recurrence rate（0.00%）significantly lower than the 2D group（7.32%），the difference was statistically significant（P<0.05）.Conclusion：Compared with 2D laparoscope，3D laparoscopy can more effectively control intraoperative blood loss，shorten urethral reconstruction time，improve the success rate of erectile function retention，and reduce the incidence of postoperative complications.More obvious，worthy of clinical promotion.

Key words: prostatectomy, 3D laparoscopy, 2D laparoscopy, therapeutic effect