临床外科杂志 ›› 2024, Vol. 32 ›› Issue (10): 1069-1073.doi: 10.3969/j.issn.1005-6483.2024.10.017

• 论著 • 上一篇    下一篇

有限接触动力加压钢板治疗肱骨近端骨折预后不良的风险因素分析及Nomogram预测模型

张刚 张玉智 解琛   

  1. 250031 解放军联勤保障部队第九六〇医院骨科
  • 收稿日期:2023-12-13 出版日期:2024-11-07 发布日期:2024-11-07
  • 通讯作者: 解琛,Email:ripplitxie@163.com

Construction and verification of nomogram model for predicting prognosis and complications of patients with humeral fracture treated with LC-DCP treatment

ZHANG Gang,ZHANG Yuzhi,XIE Chen   

  1. Department of Orthopedics,PLA Joint Logistics Support Force 960 Hospital,Jinan City,Shandong Province 250031,China
  • Received:2023-12-13 Online:2024-11-07 Published:2024-11-07

摘要: 目的分析影响肱骨近端骨折预后的危险因素,并据此构建预测有限接触动力加压钢板(LC-DCP)治疗肱骨近端骨折预后的Nomogram模型。方法 2013年1月~2020年12月本院接受LC-DCP治疗的肱骨近端骨折病人372例,随机按照7〖DK〗∶3分为建模队列(260例)与验证队列(112例),根据术后6个月的肩关节Neer评分分为预后良好组(≥70分)和预后不良组(<70分)。行单因素分析,差异有统计学意义的因素进一步进行多因素Logistic回归分析,得出影响LC-DCP治疗肱骨骨折预后的危险因素,并据此建立Nomogram模型。分别在建模队列和验证队列采用校准曲线和ROC曲线对该Nomogram模型进行交叉验证。结果 372例肱骨近端骨折病人经LC-DCP治疗后,预后不良发生率为20.43%(76/372)。单因素分析显示,预后良好组的年龄、切口长度、术中出血量、术后开始功能锻炼时间和术后并发症显著低于预后不良组(P<0.05)。多因素Logistic回归分析显示,年龄≥60岁、切口长度≥5 cm、术中出血量≥110 ml、术后开始功能锻炼时间≥7天以及有术后并发症是影响LC-DCP治疗肱骨近端骨折疗效的独立危险因素(P<0.05)。该Nomogram模型的校准曲线和ROC曲线显示,内部验证与外部验证的校准曲线斜率均接近1,内部验证的ROC下面积为0.823,外部验证的曲线下面积为0.839。结论基于年龄、切口长度、术中出血量、术后并发症以及术后开始功能锻炼时间构建的预测LC-DCP治疗肱骨近端骨折疗效的Nomogram模型,具有较好的准确度和稳健性。

关键词: 有限接触动力加压钢板; 肱骨骨折; 预后; Nomogram

Abstract: Objective To collect the clinical data of patients and construct a nomogram model to predict the prognosis of patients with humeral fracture treated with limited contact dynamic compression plate(LC-DCP).Methods A total of 372 patients with humeral fractures who received LC-DCP in our hospital from January 2013 to December 2020 weree randomly divided into a modeling cohort(n=260) and a validation cohort(n=112) according to 7∶3.Logistic regression model was used to analyze the data of the modeling cohort,and a Nomogram model was established according to the results of the influencing factors of poor prognosis of LC-DCP treatment for patients with humerus fractures.Nomogram was validated internally(modeling cohort) and externally(validation cohort) using calibration curve and ROC curve.Results The incidence of poor prognosis was 20.43%(76 / 372) in 372 patients with humeral fracture treated with LC-DCP.Univariate analysis showed that the age, incision length, intraoperative blood loss, time to start functional exercise and postoperative complications in the good prognosis group were significantly lower than those in the poor prognosis group (P<0.05).Multivariate Logistic regression analysis showed that age ≥60 years old, incision length ≥5 cm, intraoperative blood loss ≥110 ml, start time of functional exercise ≥7 days after surgery, and postoperative complications were independent risk factors for the efficacy of LC-DCP in the treatment of proximal humeral fracture (P<0.05).The calibration curve and ROC curve of the Nomogram model showed that the slope of the calibration curve for internal verification and external verification was close to 1, and the area under ROC for internal verification and external verification was 0.823 and 0.839 respectively.Conclusion The Nomogram model established in this study based on postoperative complications,intraoperative blood loss,age,postoperative functional exercise start time and incision length is effective and discriminative.

Key words: LC-DCP therapy; humeral fracture; prognosis; Nomogram

No related articles found!
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!