关键词: 乳腺癌；整形保乳手术；复发

Abstract: Objective To explore the effectiveness and recurrence rate of oncoplastic breast surgery in the treatment of early-stage breast cancer.Methods A retrospective study was conducted on 50 patients who underwent oncoplastic breast surgery (observation group) and 50 patients who underwent conventional breast-conserving surgery (control group) for early-stage breast cancer between January 2017 and June 2019,selected according to admission order and inclusion/exclusion criteria.The surgical time,intraoperative blood loss,length of hospital stay,immune function indicators,postoperative complication rate,excellent appearance rate of the breast,quality of life score,survival rate,and recurrence rate were compared between the two groups.Results The average intraoperative blood loss in the observation group was (40.27±11.35) ml,which was lower than that in the control group (74.65±21.84) ml.The observation group had shorter surgical time (51.28±6.79) min and hospital stay (7.41±1.87) days compared to the control group (P<0.05).CD3+ and CD4+/CD8+ levels were higher in the observation group than in the control group after surgery (P<0.05).The observation group had a lower incidence of postoperative complications compared to the control group (2.00% vs 14.00%,P<0.05).The excellent appearance rate of the breast was higher in the observation group than in the control group (100% vs 90%,P<0.05).After surgery,the quality of life scores in all factors were higher in the observation group than in the control group (P<0.05).There was no significant difference in postoperative survival rate and recurrence rate between the observation and control groups (P＞0.05).Conclusion Oncoplastic breast surgery,compared to conventional breast-conserving surgery,can effectively improve the appearance of the breast,reduce surgical trauma and immune function damage,decrease postoperative complications,and enhance the quality of life of patients with early-stage breast cancer without affecting their long-term prognosis or increasing the recurrence rate.

Key words: breast cancer; plastic breast-conserving surgery; recur