关键词: 术前栓塞, 手术, 实性, 血管母细胞瘤, Meta分析

Abstract: Objective To evaluate the clinical efficacy and safety of preoperative endovascular embolization of Solid Hemangioblastomas. Methods The data bases including Wan Fang,CNKI(China National Knowledge Infrastructure),VIP Database,PubMed、Medline、Springer were searched for the related studies.Two independent surgeons assessed trails for eligibility and quality,and all data marching the standards were abstracted for Meta-analysis by RevMan 5.3. Results 8 randomized controlled trails (RCT) were included.Selected analysis of embolized and non-embolized groups of Solid Hemangioblastomas were observed for variables of clinical efficacy in surgery time,number of blood loss and transfusions,complete resection,there were statistical difference.(P<0.000 01，WMD=-1.18, 95%CI[-1.16,-0.71];P<0.000 01，WMD=-464.17,95%CI[-492.17,-437.24];P<0.000 01， WMD=-238.81,95%CI[-282.84,-194.77];P<0.006，RR=1.17,95%CI[1.05，1.31]). Conclusion The preoperative endovascular embolization is beneficial for Hemangioblastomas because it can shorten the time of surgery,diminish the necessity of intra-operative blood loss and transfusion,it also raises the ratio of complete resection of Solid Hemangioblastomas.

Key words: preoperative embolization, surgery, solid, hemangioblastomas, meta-analysis