临床外科杂志 ›› 2023, Vol. 31 ›› Issue (6): 524-527.doi: 10.3969/j.issn.1005-6483.2023.06.007

• 论著 • 上一篇    下一篇

简化弗尔涅坏疽严重性指数量表判断肛周坏死性筋膜炎预后的临床价值

  

  1. 200032 上海中医药大学附属龙华医院肛肠科 
  • 收稿日期:2022-08-08 出版日期:2023-06-20 发布日期:2023-06-20
  • 通讯作者: 姚一博,Email:elevenzoe@163.com
  • 基金资助:
    国家自然科学基金(82174373,81603625)

Clinical value of simplified Fournier’s gangrene severity index in predicting the prognosis of perianal necrotizing fasciitis

  1. Department of Anorectal Surgery,LongHua Hospital Shanghai University of Traditional Chinese Medicine,Shanghai 200032, China
  • Received:2022-08-08 Online:2023-06-20 Published:2023-06-20

摘要: 目的 探讨简化弗尔涅坏疽严重性指数(Simplified Fournier’s Gangrene Severity Index,SFGSI)判断肛周坏死性筋膜炎患者预后的临床价值。方法 2010年1月1日~2022年1月1日确诊并经过手术治疗的肛周坏死性筋膜炎病人52例,根据临床结局将病人分为生存组和死亡组,Logistic回归分析肛周坏死性筋膜炎的死亡危险因素,采用受试者工作特征曲线以及Hosmer-Lemeshow拟合优质评估SFGS估量表的辨别力和校准度。结果 本研究共采集52例病人信息,生存组(A组)43例,死亡组(B组)9例,总死亡率17.31%。生存组和死亡组年龄、血清钾和SFGSI评分比较差异有统计学意义(P<0.05)。病人每增龄5岁,死亡危险度是前一年龄组的2.033倍;血清钾异常死亡风险是正常组的3.656倍;SFGSI>2时,病人死亡危险度是SFGSI≤2时的6.429倍。SFGSI量表判断病人预后有较高的准确性,AUC=0.829(0.709~0.949)。结论 SFGSI可用于帮助判断肛周坏死性筋膜炎病人的死亡危险性。

关键词: 肛周坏死性筋膜炎, 预后评估, SFGSI, 预测价值

Abstract: Objective To explore the clinical value of simplified Fournier’s gangrene severity index(SFGSI) in accessing the prognosis of patients with perianal necrotizing fasciitis. Methods 52 patients with perianal necrotizing fasciitis who were diagnosed and underwent surgical treatment from January 1, 2010 to January 1, 2022.The patients were divided into survival group and death group according to the clinical outcome.We retrospectively analyzed the risk factors of death and the discrimination and calibration of SFGSI in accessing the prognosis of patients with perianal necrotizing fasciitis. Results A total of 52 patients were collected in this study,and they were grouped as survival group(group A,43 cases) and non-survival group(group B,9 cases).The total mortality was 17.31%.There were significant differences in age,potassium and SFGSI scores between survival group and death group(P<0.05):For every 5 year increase in age,the risk of death increased 2.033 times.The risk of death from abnormal potassium group was 3.656 times higher than normal group.When SFGSI > 2 ,the risk of death was 6.429 times higher than that of patients with SFGSI≤2.SFGSI has high accuracy in predicting the prognosis of patients,AUC =0.829(0.709-0.949). Conclusion SFGSI can be used to help predict the prognosis and death risk of perianal necrotizing fasciitis.

Key words: perianal necrotizing fasciitis, prognosis evaluation, simplified Fournier’s gangrene severity index, clinical value

[1] 胡明玉 苗祥 潘书鸿. 改良结肠渗漏评分对左结肠直肠手术病人吻合口漏的预测价值[J]. 临床外科杂志, 2022, 30(2): 175-178.
[2] 张玉茹 李非. 肛周坏死性筋膜炎的诊治进展[J]. 临床外科杂志, 2012, 20(1): 69-69.
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