关键词: 肺叶切除术, 亚肺叶切除术, 肺癌, 肺功能, 术后复发率

Abstract: Objective To compare the clinical effect of lobectomy and sublobar lobectomy on pulmonary function and recurrence in elderly patients with NSCLC.
Methods 164 elderly patients with lung cancer from January 2014 to December 2015 in our hospital were analyzed,included 68 patients with sublobar lobectomy(A group),96 patients with lobectomy(B group).The duration of operation,intraoperative blood loss,thoracic drainage time,lung function,postoperative recurrence rate were observed and compared.
Results The duration of operation,intraoperative blood loss,thoracic drainage time and drainage volume of patients in A group were(140.83±32.17) min,(78.45±25.64) ml,(5.18±1.17) min,(786.31±157.42) ml,which were less than B group(P<0.05).And after surgery 3 d,the force vital capacity(FVC),forced expiratory volume in one second(FEV1),FEV1%pre,peak expiratory flow(PEF) of patients in A group were higher than B group(P<0.05).There was no difference on complications and postoperative 3-year recurrence rate between two groups(35.29% vs.25.0%)(P>0.05).
Conclusion The recurrence rate of sublobectomy is similar to that of lobectomy,but the complication rate of sublobectomy is lower and the pulmonary function would be less affected in elderly patients with early NSCLC.

Key words: lobectomy, sublobar lobectomy, lung cancer, lung function, recurrence rate