关键词: 深静脉血栓形成, 腔内治疗, 导管溶栓, 机械血栓清除, 血栓后综合征

Abstract: Objective：To explore the effects of different intracavitary treatments on the prognosis of acute iliofemoral vein thrombosis.Methods：The patients with acute iliofemoral vein thrombosis(Iiiacfemoralvenousthrombosis,IFVT) diagnosed by color Doppler ultrasound in our center from January 2015 to September 2016 were retrospectively analyzed.Different methods of intracavitary treatment were adopted:catheter directed thrombolysis(CDT),AngioJet pharmacomechanical thrombectomy(PMT) and pharmacomechanical thrombectomy combined with catheter directed thrombolysis(PMT+CDT).The followup data of 12 months,24 months,36 months and 48 months after operation were statistically analyzed to evaluate the recurrence rate of venous thrombosis,the incidence and severity of postthrombotic syndrome(PTS).Results：During the 48month followup,the overall thrombus recurrence rate of 102 patients was 19.6% and the incidence of PTS was 22.5%.During the followup,there was no significant difference in the recurrence rate of thrombus and the incidence of PTS among the three groups(P＞0.05).When the patients were followed up for 24 months or more,the Villalta scores in the PMT group and the PMT+CDT group were significantly lower than those in the CDT group,and there was significant difference among the three groups(P<0.05).Conclusion：The three endovascular therapy methods can effectively remove thrombus,protect venous function,and play an active role in preventing the recurrence of DVT and the occurrence of PTS.During the followup of 24 months or more,the severity of PTS in the PMT group and the PMT+CDT group was significantly lower than that in the CDT group.

Key words: deep venous thrombosis, endovascular therapy, catheter directed thrombolysis, pharmacomechanical thrombectomy, postthrombotic syndrome