关键词: 敏感度；特异度；继发性下肢淋巴水肿；评估工具

Abstract: Objective To study the sensitivity and specificity of Lymphoedema Functioning,Disability and Health Questionnaire for Lower Limb Lymphoedema (Lymph ICF-LL) and Lymphoedema Quality of Life Questionnaire (LYMQOL),and to explore the optimal cutoff score of the scales,in order to better identify secondary lower limb lymphoedema.Methods 62 patients with secondary lower limb lymphoedema and 37 patients without lymphedema after gynecological cancer operation was collected.Spearman test was used to evaluate the correlation between the scores of the two scales and the Lower Extremity Lymphedema Index (LEL index).Receiver operating characteristic (ROC) was used to evaluate the predictive diagnostic efficacy of the two scales.Results Correlation analysis showed that Lymph ICF-LL score was positively correlated with LEL index (r=0.478,P<0.05),and LYMQOL score was positively correlated with LEL index (r=0.346,P<0.05).Both scales had high accuracy,sensitivity and specificity in detecting secondary lymphedema of lower limbs.The area under the ROC curve of Lymph ICF-LL score in predicting was 0.926 (P<0.05),the optimal cut-off value was 20.1 points,the sensitivity was 83.9% and the specificity was 91.9%.The area under the ROC curve of LYMQOL score in predicting was 0.883 (P<0.05),the optimal cut-off value was 1.9 points,the sensitivity was 80.6%,and the specificity was 83.8%.Conclusion Lymph ICF-LL and LYMQOL have high specificity and sensitivity in the diagnosis of secondary lower limb lymphoedema.The two scales can be used as one of the diagnostic Methods for secondary lower limb lymphoedema.

Key words: sensitivity; specificity; secondary lower limb lymphoedema; assessment Instrument