关键词: 纤维支气管镜, 创伤性颅脑损伤, 肺部感染, 临床疗效

Abstract: Objective To investigate the clinical effect of bedside fiberoptic bronchoscopy on patients with traumatic brain injury complicated with pulmonary infection undergoing mechanical ventilation. Methods From July 2018 to July 2022, 82 patients with traumatic craniocerebral injury complicated with pulmonary infection treated in our hospital were enrolled,42 patients with routine sputum aspiration were set as the control group,and 40 patients with bedside fiber bronchoscopy were set as the experimental group.Sputum samples were collected from both groups for examination and culture,and clinical data such as chest CT lesion absorption time,mechanical ventilation time,anti-infection course,ICU stay time were recorded.Driving pressure (△P),oxygenation index (OI),respiratory mechanical index and detection rate of effective pathogens were calculated.GOS-E score was followed up 6 months after injury. Results The total effective rate of the experimental group (95.00%) was higher than that of the control group (78.57%)(P<0.05).The ICU stay time,mechanical ventilation time,focus absorption time,driving pressure (△P),oxygenation index (OI),respiratory mechanics index and GOS-E score of the experimental group were significantly improved compared with the control group,and the differences were statistically significant (P<0.05). Conclusions  The implementation of bronchoscopy in ICU patients with traumatic craniocerebral injury and pulmonary infection can effectively improve pulmonary ventilation,lung dynamic compliance,and cerebral blood perfusion,which is helpful for clinical brain-lung conflict management and neurological prognosis.

Key words: fiberoptic bronchoscope, traumatic brain injury, pulmonary infection, clinical efficacy