临床外科杂志 ›› 2021, Vol. 29 ›› Issue (5): 454-457.doi: 10.3969/j.issn.1005-6483.2021.05.016

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消化道神经鞘瘤81例分析

  

  1. 130033 长春, 吉林大学中日联谊医院胃肠结直肠肛门外科
  • 出版日期:2021-05-20 发布日期:2021-05-20

Analysis of 81 cases of gastrointestinal tract schwannoma

  1. Department of Gastrointestinal Colorectal and Anal Surgery,China-Japan Union Hospital of Jilin University,Changchun 130033,China
  • Online:2021-05-20 Published:2021-05-20

摘要: 目的  回顾并总结消化道神经鞘瘤的临床特点。
方法  以神经鞘瘤为检索词,检索在2018~2020年期间发表在知网数据库、万方数据库、Pubmed数据库的关于消化道神经鞘瘤的临床病例报道,进行统计和总结。
结果  81例消化道神经鞘瘤病人多以女性为主,年龄31~84岁,胃部多发,肿瘤直径0.2~9cm;临床表现多以腹痛、腹胀为首发症状,大部分病人无明显症状,术前诊断准确率仅为8.6%;所有病人术后免疫组化表达均表现为S-100阳性;完整切除肿物或胃(肠道)部分切除术是主要的手术方式,术后无复发和转移。
结论  消化道神经鞘瘤是少见于消化道的良性肿瘤,其术前误诊率高,免疫组化S-100阳性是其诊断的金标准;手术治疗是主要方式,术后极少发生复发和转移。

关键词: 消化道神经鞘瘤, 内镜超声检查, S-100, 误诊

Abstract: Objective Summarize the clinical characteristics of gastrointestinal tract schwannoma.
Methods Using schwannoma as the search term,the clinical case reports of gastrointestinal tract schwannomas published in the CNKI database,Wanfang database,and Pubmed database during 2018-2020 were searched,and statistics and summary were made.
Results The 81 patients with gastrointestinal tract schwannoma were mostly female,aged between 31-84 years old and most of them occur in the stomach.The diameter of the tumor was between 0.2-9 cm.The clinical manifestations were mostly abdominal pain and bloating as the first symptoms,but most patients had no obvious symptoms.The accuracy of preoperative diagnosis was only 8.6%.All patients showed positive s-100 immunohistochemical expression after surgery.Complete resection of the mass or partial gastric (colorectal) resection was the main surgical method,and there was no recurrence or metastasis after surgery.
Conclusion Gastrointestinal  tract schwannoma is a benign tumor that is rare in the gastrointestinal tract.It has a high preoperative misdiagnosis rate.S-100 positive is the gold standard for diagnosis;surgical treatment is the main method,and the prognosis is rarely recurrence and metastasis.

Key words: gastrointestinal tract schwannoma, endoscopic ultrasonography, S-100, misdiagnosis

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