关键词: 主动脉夹层动脉瘤, D-二聚体, C-反应蛋白, 假腔容积, 假腔长度

Abstract: Objective The study was the quantitative relationship between the D-dimer（DD）and C-reactive protein（CRP）levels and the geometric parameters of the false lumen in the DeBakey III aortic dissection aneurysm（ADA）patients to understand the patient's condition and make a preliminary judgment on the prognosis.Methods 35 patients were diagnosed as DeBakey type ⅢADA in Northern Jiangsu People's Hospital from January 2012 to January 2018 were selected，and clinical data such as DD and CRP values before and after surgery were collected，and aorta CTA data were measured with GE Healthcare Volume ViewerTM post-processing software to obtain the values of false lumen volume（FLV），false lumen length （FLL），and maximum false lumen diameter（MFLD）before and after surgery，and then correlation studies were carried out. Results The analysis showed that the proportion of DD and CRP values above the upper limit of normal after surgery was higher than before（94.3% vs 100% and 40% vs 94.3%）and the postoperative average value was also higher than before（3.76±3.88 vs 5.14±3.68 and 35.35±54.92 vs 56.98±34.16）The DD and CRP values of the type DeBakeyⅢ ADA patients decreased after operations（74.3%），but the FLL，MFLD and FLV values decreased in the vast majority（94.3%）of type DeBakey III ADA patients; The changes of CRP，FLL，MFLD and FLV after operation were significant（P<0.05），but the DD value before and after surgery did not change significantly（P＞0.05）; Preoperative DD level was weakly associated with preoperative FLL，and postoperative CRP level was weakly associated with postoperative FLV.Conclusion DD and CRP value could reflect the trend of geometric parameters of type DeBakey III ADA false lumen to a certain extent，and make a preliminary judgment on the prognosis.

Key words: Aortic dissection aneurysm, D-dimer, C-reactive protein, False lumen length, Maximum false lumen diameter