关键词: 列线图预测模型, 酒精性肝硬化, 胆囊结石, 腹腔镜胆囊切除术, 胃肠道症状

Abstract: Objective To construct the nomographic chart model for gastrointestinal symptoms after operation of alcoholic cirrhosis complicated with cholecystolithiasis and to explore its predictive value.Methods One hundred patients with ALC complicated with gallbladder stones who received treatment in our hospital from October 2021 to October 2022 were selected for surgical treatment,collect relevant patient data and analyze the occurrence of postoperative gastrointestinal symptoms and their scores,based on the evaluation results of gastrointestinal symptoms,patients are divided into mild and moderate to severe groups,analyze the factors affecting the severity of postoperative gastrointestinal symptoms,and construct a column chart prediction model;evaluate and validate the model using ROC curves,calibration curves,and DCA curves.Results  Patients with mild to moderate to severe postoperative gastrointestinal symptoms showed statistically significant differences in age,intraoperative blood pressure abnormalities,early postoperative eating,early postoperative bed movement,advanced analgesia,anxiety selfassessment scale (SAS) scores,postoperative use of gastrointestinal motility drugs,and surgical time (P<0.05);Age,intraoperative abnormal blood pressure,early postoperative eating,early postoperative bed movement,preemptive analgesia,surgical time,SAS score,and gastrointestinal motility promoting drugs of the model group were influencing factors for the severity of postoperative gastrointestinal symptoms in patients (P<0.05);building a column chart prediction model based on the above factors,ROC,calibration curve,and DCA indicate that the prediction model has good predictive ability and clinical effectiveness,and has good accuracy and differentiation.Conclusion  The factors influencing the severity of gastrointestinal symptoms after surgery for ALC combined with gallbladder stones include age,abnormal intraoperative blood pressure,early postoperative feeding,early postoperative bed exercise,duration of surgery,over the counter analgesia,SAS score,and postoperative use of pro-gastrointestinal motility drugs,and the above factors were constructed into a columnar graph prediction model with good predictive efficacy and clinical utility.

Key words: nomographic chart predictive model, alcoholic cirrhosis, gallbladder stones, laparoscopic cholecystectomy, gastrointestinal symptom