关键词: 控制性低中心静脉压, 肝切除术, 碳酸氢钠林格液, 内环境, 苏醒

Abstract: Objective To analyze the clinical effects of sodium bicarbonate ringer’s solution in patients undergoing controlled low central venous pressure hepatectomy.Methods 80 Patients undergoing hepatectomy in our hospital from October 2021 to May 2022 were randomly divided into lactate ringer’s group (LR group) and sodium bicarbonate ringer’s group (BR group) according to the different types of intraoperative infusion.All patients with partial liver resection were treated with controlled low central venous pressure.The operation time,hilar block time,bleeding volume,infusion volume,urine volume,application of vasoactive drugs,postoperative eye opening time,extubation time,PACU residence time and the number of delayed recovery cases were compared between the two groups.The arterial blood gas and lactate values between the two groups were compared at the time before the induction of anesthesia (T-1),hepatectomy completed immediately (T-2) and the end of surgery (T-3).Results Lactate values  were significantly lower(P<0.05) while PH,HCO-3 and BE were significantly higher in the BR group than those in the LR group (P<0.05) at T-2 and T-3.Urine volume in the BR group was significantly excess in the LR group (P<0.05).Postoperative eye opening time,extubation time,PACU residence time and the number of delayed recovery cases in the BR group were significantly less than those in the LR group (P<0.05).Conclusion Sodium bicarbonate ringer’s solution can effectively maintain the acid-base balance stability of the body,reduce the lactate value,reduce the burden of the liver,increase the urine volume,and shorten the time of awakening and extubation in patiens undergoing controlled low central venous pressure hepatectomy.

Key words: Controlled low central venous pressure, Hepatectomy, Sodium bicarbonate ringer’s solution, Internal environment, Recovery