关键词: 腹腔镜下右半结肠癌根治术, 胃肠功能紊乱, 危险因素, 风险预测

Abstract: Objective：To explore the risk factors of gastrointestinal dysfunction after laparoscopic radical resection of right colon cancer，and to establish a risk prediction model for intestinal dysfunction.Methods：The clinical data of 161 patients undergoing laparoscopic radical resection of right colon cancer were analyzed retrospectively from January 2016 to April 2019 in the department of gastrointestinal surgery，Renmin Hospital of Wuhan University.The independent risk factors for the occurrence of gastrointestinal dysfunction after operation were determined by single factor and multifactor analysis.The sensitivity and specificity of ROC and AUC were calculated.Results：The incidence of gastrointestinal dysfunction was 17.3%.Multivariate analysis showed that preoperative malnutrition（P<0.05）and preoperative incomplete intestinal obstruction（P<0.05）were independent risk factors for postoperative gastrointestinal dysfunction.Based on this，a predictive model of postoperative gastrointestinal dysfunction was established.The area under ROC curve was 0.750（95% CI：0.658～0.841）.The sensitivity and specificity of the curve were 0.786 and 0.639，respectively.Conclusion：Preoperative malnutrition and preoperative incomplete intestinal obstruction are independent risk factors for gastrointestinal dysfunction after laparoscopic radical resection of right colon cancer.The sensitivity and specificity of the established prediction model are high，which can provide reference for the prediction of gastrointestinal dysfunction after laparoscopic radical resection of right colon cancer.

Key words: laparoscopic radical resection of right colon cancer, gastrointestinal dysfunction, risk factors, risk prediction