关键词: 直肠间质瘤, 局部切除, 伊马替尼

Abstract: Objective To study the clinical characteristics and treatment methods of the low rectal stromal tumor.Methods The clinical and follow-up data of 32 patients with low rectal gastrointestinal stromal tumor（GIST）were analysed.Paitents with Dixon and Miles operation were called group expanded resection（14 cases），and patients with endoscopic resection，trans-anal，trans-sacral，trans-perineum resection were called group local resection（18 cases）.Compared the two groups with clinical characteristics and postoperative recurrence or metastasis.Results Operation time of group expanded resection was（152.4±46.2）min，while group local resection was（54.1±17.9）min，the blood loss of the two group was（76.1±36.6）ml and（41.1±20.3）ml，respectively；anus exhausting time of the two group was （3.8±0.6）d and （2.9±0.8）d，respectively；hospital stay of the two group was （10.2±1.6）d and （6.3±1.3）d，respectively（all P<0.05）.There was no significant difference such as surgical complications，local recurrence and distant metastasis between the two groups.Conclusion Low rectal stromal tumor treated by local excision and imatinib did not increase the risk of local recurrence and distant metastasis，but the operation time，blood loss，hospitalization days significantly reduced，It is a safe and effective strategy to low rectal stromal tumor.

Key words: rectal stromal tumor, local resection, imatinib