关键词: 吸入性麻醉,  ,  , 开胸手术,  , cTnI,  , 心肌酶

Abstract:    Objective    To investigate the effect of sevoflurane inhalation anesthesia on postoperative serum cTnI and myocardial enzyme levels in patients undergoing thoracotomy.Methods  62 cases of patients undergoing thoracotomy were selected for this study.The patients were randomly divided into the observation group and the control group.In the observation group，the patients were treated with sevoflurane inhalation anesthesia.In the control group，patients received propofol intravenous anesthesia.The Cardiac troponin I（cTn I）levels and myocardial enzyme levels at 7 time points of before induction of anesthesia，10 minutes after the start of CPB（T1），aortic opening immediately（T2），30 minutes after the opening of the aorta（T3），1 hour after the opening of the aorta（T4），and 6 hours after CPB shutdown（T5）and 24 hours after CPB shutdown were recorded and compared between the two groups of patients.Results  The cTnI concentrations of the two groups of patients showed an increasing trend at seven time points.The cTnI concentration of the observation group at the time points of T4 and T5 was higher than those of the control group.The levels of CKMB and LDH of the observation group at the time point of T3 were lower than those of the control group，and the difference was statistically significant（P<0.05）.Conclusion  The cTnI concentration of inhaled anesthesia patients is generally lower than that of intravenous anesthesia patients.Compared with intravenous anesthesia patients，the recovery time of inhalation anesthesia patients is short，and the postoperative pain perception is relatively lower and the myocardial damage is relatively lighter，which is worthy of clinical recommendation.

Key words: inhalation anesthesia,  ,  , thoracotomy,  ,  , cTnI,  , myocardial enzymes